Is panax notoginseng safe​?

Is panax notoginseng safe​?

 

Notoginseng saponin has a long history of application in traditional Chinese medicine, at least it can be traced back to the 15th century. It was originally used to treat a variety of diseases, including hemorrhagic diseases, wounds, and cardiovascular diseases.

However, the dosage of notoginseng saponins should be confirmed by a more authoritative expert, such as the use of standardized extracts and a higher dosage, and should be used within the recommended range.

 

Panax Notoginseng​ benefits

 

Cardiovascular Health

One of the most well-researched areas of Panax notoginseng is its effects on cardiovascular health. Numerous studies have shown that Panax notoginseng may help improve blood circulation, lower blood pressure, and lower cholesterol levels. For example, a study published in the Journal of Ethnopharmacology (2015) investigated the effects of Panax notoginseng saponins in patients with coronary heart disease. The results showed that the saponins significantly improved blood flow in the coronary arteries and reduced the frequency of angina attacks.​

This study in the International Journal of Cardiology (2016) examined the effects of Panax notoginseng on blood pressure in hypertensive rats. Researchers found that treatment with Panax notoginseng extract led to a significant decrease in both systolic and diastolic blood pressure, possibly due to the herb's ability to improve endothelial function.

The anticoagulant and antiplatelet effects of Panax notoginseng are also important for cardiovascular health. By inhibiting platelet aggregation and reducing blood viscosity, it may help prevent the formation of blood clots, which are a major cause of venous thromboembolism. However, as previously mentioned, it also poses a risk of bleeding in certain individuals.

 

Anti-inflammatory and Antioxidant Effects

Inflammation and oxidative stress are underlying factors in many chronic diseases, and Panax notoginseng has been shown to possess potent anti-inflammatory and antioxidant properties. Studies have shown that ginsenosides in Panax notoginseng can inhibit the production of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β, and reduce the activity of pro-inflammatory enzymes such as inducible nitric oxide synthase (iNOS).

The antioxidant effects are attributed to the ability of Panax notoginseng to scavenge free radicals, such as superoxide anions and hydroxyl radicals, and to increase the activity of antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT). These effects may help protect cells from oxidative damage, reduce the risk of chronic diseases, and promote overall health and well-being.

 

Wound healing and tissue repair

Traditionally, Panax notoginseng has been used to treat wounds, bruises, and traumatic injuries, and modern research has supported its efficacy in promoting wound healing. Studies in animal models have shown that Panax notoginseng can accelerate the formation of new blood vessels (angiogenesis), increase collagen synthesis, and reduce the appearance of scars. These effects contribute to faster wound closure and improved tissue repair.

A study published in the Journal of Traditional Chinese Medicine (2014) evaluated the effects of Panax notoginseng powder on chronic skin ulcers in humans. The results showed that the treatment group had a significantly higher healing rate and shorter healing time compared to the control group, indicating the potential of Panax in promoting healing.

 

Panax notoginseng in a clinical setting

Several clinical trials have been conducted to assess the safety and efficacy of Panax notoginseng in various populations. A meta-analysis of clinical trials published in Evidence-Based Complementary and Alternative Medicine (2017) reviewed data from 18 studies that included over 1,500 subjects. The analysis found that Panax notoginseng was generally well tolerated, with a low incidence of adverse events. The most common side effects were mild gastrointestinal symptoms and dizziness, which were not significantly different from the placebo group in many studies.

Another important aspect of safety is the quality and purity of Panax notoginseng products. Contamination with heavy metals, pesticides, or other harmful substances may pose a risk to consumers. However, studies on commercially available Panax notoginseng extracts have shown that when produced by reputable manufacturers following good manufacturing practices (GMP), the product meets safety standards for metal.

 

Quality Assurance and Product Selection

To ensure the safety and efficacy of Panax notoginseng products, it is important to choose products from reputable manufacturers. Look for products that are standardized to contain specific levels of active ingredients, such as ginsenosides, and that have been tested for purity and quality. Certifications from independent organizations such as the US Pharmacopeia (USP), NSF International, or the European Medicines Agency (EMA) can provide additional quality assurance.

Avoid purchasing Panax notoginseng products from unknown sources or those that make exaggerated claims about their benefits. Quality products should have clear labeling that includes information about ingredients, dosage, manufacturing date, and expiration date.

 

 

Where to Purchase Panax Notoginseng Extract​?

 

If you are looking for high-quality Panax notoginseng extract, you can contact Sost Biotech. Sost Biotech is a leading provider of natural herbal extracts, committed to producing safe, pure, and effective products. Their Panax notoginseng extract is manufactured using advanced extraction techniques and undergoes strict quality control to ensure the highest standards of purity and potency.

For more information or to place an order, please contact Sost Biotech through their official website or customer service channels.​

Email:info@sostherbusa.com