Ascorbyl Tetraisopalmitate
CAS No.: 183476-82-6
Molecular Formula: C70h128o10
Molecular Weight: 1129.76
Sample: Available
Appearance: Clear Colorless Liquid
Assay: 99%
Test Method: HPLC
Shelf Life: 2 Years
Grade: Cosmetic Grade
Application: Beauty Products
1. Ascorbyl Tetraisopalmitate Feature
As a lipid-soluble derivative of vitamin C, Ascorbyl Tetraisopalmitate (VC-IP) delivers a dual-action antioxidant mechanism:
Direct Radical Scavenging: Neutralizes reactive oxygen species (ROS) caused by UV rays, pollution, and environmental stress, reducing lipid peroxidation and DNA damage.
Endogenous Defense Boost: Enhances the activity of superoxide dismutase (SOD) and other antioxidant enzymes to strengthen the skin's self-protective barrier.
Research Insight: VC-IP demonstrates 16.5x higher transdermal absorption than water-soluble vitamin C, enabling long-lasting antioxidant effects in the dermis.

2. Ascorbyl Tetraisopalmitate for Skin
Ascorbyl Tetraisopalmitate stands out from traditional vitamin C with its low irritation and high stability:
pH-Neutral Design: Activates without an acidic environment, minimizing redness and sensitivity risks.
Thermal Stability: Maintains efficacy above 40°C, suitable for diverse formulations (e.g., sunscreens, facial oils).
Regulatory Approval: Approved by Japan's Ministry of Health as a quasi-drug active ingredient (3% concentration) and registered in South Korea for brightening effects (2% concentration).
3. Ascorbyl Tetraisopalmitate benefits
VC-IP achieves comprehensive skin tone management through a three-pronged approach:
Melanin Inhibition: Directly blocks tyrosinase activity to reduce melanin transfer.
Exfoliation & Renewal: Accelerates keratinocyte turnover to fade existing spots and dullness.
Synergistic Enhancement: Boosts whitening efficacy by 30%+ when combined with niacinamide or tranexamic acid.

Technical Specifications
| Parameter | Value |
|---|---|
| Purity | ≥97% (HPLC tested) |
| Density (20℃) | 0.930-0.943 g/cm³ |
| Refractive Index | 1.459-1.465 (25℃) |
| Heavy Metals | Lead <10ppm, Arsenic <2ppm |
Recommended Dosage:
Whitening Serums: 1%-3%
Sunscreens: 0.5%-2% (enhances photoaging protection)
Repair Creams: 0.3%-1% (synergizes with ceramides for barrier repair)

application case
Ascorbyl tetraisopalmitate is an active ingredient in PROYA Nourishing Essential Oil, which also contains a variety of plant extract essential oils, such as jojoba seed oil, macadamia nut oil, and meadowfoam seed oil. These ingredients work together to provide moisturizing, anti-oxidation, anti-aging, and soothing skin care effects. In addition, tocopherol (vitamin E) is added to the product, which has antioxidant, anti-wrinkle, and firming effects, and has a low acne risk level.
Zanyan brand has launched a recombinant mussel mucin rapid repair mask containing ascorbic acid tetraisopalmitate. This mask is rich in a variety of ingredients, including glycerol, dipropanol, octanoic acid/decanoate triglyceride, panthenol, butanediol, phenoxyethanol, arginine, cetylstearyl glucoside, in addition to ascorbic acid tetraisopalmitate. These ingredients work together to give the mask moisturizing, anti-oxidation, soothing, repairing, tightening and other multiple effects, aiming to provide comprehensive care for the skin. Ascorbic acid tetraisopalmitate mainly plays an antioxidant and anti-aging role.
Contact Us Today
As a manufacturer in cosmetic ingredients, Sost Biotech stocks 1kg aluminum bottles and 25kg drums for immediate delivery, supporting small-batch trials and custom solutions.
Email:info@sostherbusa.com

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