Polydeoxyribonucleotide(PDRN) Powder
INCI name: Sodium DNA
Stock concentration: 5000ppm
Appearance: White or off-White Powder
Purity: >98%
Addition amount: 4%-100%
Solubility: Slightly soluble in water, insoluble in ethanol
Storage conditions: 2C-8C, avoid light
Shelf life: 2 years
What Is PDRN Powder?
Polydeoxyribonucleotide (PDRN) is a biologically active polynucleotide mixture, and its main source is the sperm cells of rainbow trout (Oncorhynchus mykiss) and salmon (Oncorhynchus keta). Through precise extraction and purification technology, DNA fragments that meet specific specifications can be obtained. It is worth noting that the similarity between PDRN and human DNA bases is as high as 98%, and this high homology lays the foundation for its biological function. A large number of previous studies have confirmed that PDRN has strong biological properties and has shown significant effects in anti-inflammatory repair, optimizing skin texture, and promoting tissue regeneration. Therefore, it has attracted much attention in the fields of biomedicine and beauty skin care.

Spec.
| Item | English Translation |
|---|---|
| Product Name | Polydeoxyribonucleotide |
| English Name | Polydeoxyribonucleotide (PDRN) |
| INCI Name | Sodium DNA |
| Stock Solution Concentration | 5000ppm |
| Addition Amount | 4%~100% |
| Precautions | Avoid contact with strong acids, strong alkalis, and strong oxidants as much as possible during use. |
| Solubility | Slightly soluble in water, insoluble in ethanol. |
| Storage Conditions | 2℃-8℃, protected from light. |
| Shelf Life | 2 years |
PDRN's excellent tissue compatibility
One of the core advantages of PDRN (polydeoxyribonucleotide) in the biomedical field is its extremely high tissue compatibility. This characteristic stems from a high degree of genetic homology-scientific research confirms that the DNA sequences of humans and fish are as high as 98% similar. This near-homologous genetic basis allows PDRN to circumvent the immune system's "foreign body recognition" mechanism upon entry into the body, preventing rejection or inflammatory responses, laying a key foundation for its application in tissue repair.
Unlike other exogenous repair ingredients, PDRN's molecular structure closely matches the body's own nucleic acid fragments. Upon entry, it is rapidly recognized and accepted by cells, participating in normal physiological metabolism. Unlike some synthetic compounds, it does not form "foreign body deposits" in the body, nor does it require complex carriers to establish a positive interaction with tissue cells. This is a core reason for its highly recognized safety in clinical applications.

Application
In the field of medical beauty, PDRN (Salmon DNA Sodium) has become a highly recognized star ingredient with its excellent efficacy. In the "Salmon Water Light Medical Beauty Project", it can deeply act on the skin, accurately repair damaged and sensitive skin, effectively relieve sensitive symptoms by strengthening the skin barrier function, and play a dual role of anti-oxidation and anti-aging, helping the skin to glow with health.
When applied to skin care products, PDRN also shows strong skin care strength. It can significantly reduce the level of inflammatory factors, relieve skin inflammation problems from the root, activate the skin's self-repair mechanism, rebuild an efficient defense barrier, and provide professional repair solutions for sensitive, inflamed and other problem skin. In addition, PDRN can also stimulate the regeneration of collagen, improve skin microcirculation, promote the orderly growth of new cells, accelerate the metabolic renewal of damaged cells, and awaken the vitality of aging cells, providing targeted improvements for dry, rough, wrinkled and other skin problems, so that the skin is hydrated and elastic from the inside out.

What can PDRN powder be used with?
Hyaluronic acid (HA) compound efficacy: The combination of PDRN powder and HA is a golden combination. HA has a strong water-retaining and filling effect, which can instantly fill skin depressions such as acne marks and quickly improve appearance. At the same time, PDRN works from the biological activity level, continuously stimulating collagen remodeling and promoting long-term repair and regeneration of skin tissue. The combination of the two achieves an ideal balance between "immediate improvement" and "long-term repair".
Growth factor synergy: The combination of Polydeoxyribonucleotide(PDRN) Powder with growth factors such as EGF (epidermal growth factor) and FGF (fibroblast growth factor) can significantly improve the migration and proliferation ability of fibroblasts. In the complex wound repair process, these components interact with each other to promote cell regeneration and tissue reconstruction, shorten the recovery cycle, and improve the quality of repair.
Enhanced serum protein binding: Serum proteins such as albumin and transferrin have amazing synergistic effects when used in combination with PDRN. The IGF-1 carried by albumin forms a positive feedback mechanism with the A2A receptor activated by PDRN, significantly increasing the collagen synthesis rate by 55%. In addition, the transferrin-Fe³⁺ complex enhances the antioxidant enzyme induction ability of PDRN, increases the ROS (reactive oxygen) scavenging efficiency by 70%, and significantly improves the skin's antioxidant and self-repair abilities.
Improvement of joint function in physical therapy
Synergistic effect of microneedle radiofrequency (MRF): The combined use of microneedle radiofrequency and PDRN brings a new breakthrough in skin anti-aging. The minimally invasive channel formed by microneedles in the skin significantly promotes the penetration of PDRN into the dermis, allowing its active ingredients to fully function. At the same time, the heat energy generated by radiofrequency instantly shrinks collagen and activates the collagen regeneration mechanism, thereby achieving the dual effects of firming and regenerating the skin.
Combined repair after laser surgery: Using Polydeoxyribonucleotide(PDRN) Powder after laser treatment can effectively reduce side effects such as postoperative erythema and inflammation, accelerate the repair process of the epidermal barrier, reduce the risk of postoperative infection, help the skin return to a healthy state faster, and improve the overall effectiveness and safety of laser treatment.
Polydeoxyribonucleotide(PDRN) Powder Supplier
Xi'an Sost Biotech is a factory that produces cosmetic ingredient, and organic products. We follow the healthy and green production concept and are committed to developing advanced production technologies to provide customers with High-end and safe raw material powder with considerate and guaranteed service and high cost.
Contact Us:info@sostherbusa.com

Company profile
1.Founded and main function
There Xi an Sost Biotech Co., Ltd, is a top supplier in Xi' an,China, which was founded in 2002.
We are in the Plant extract industry over 21 years,it integrates R & D,Manufacturing,Sales and one-stop Services.

2.Our Factory
Our company has 2 factories ( covering a total area of 400,00 square meters ),there are about 100 employees,we have about 5 production lines with automatic equipments,a big R&D team with 30 people,5 sales channels,2 labs and 30 patents.
The Annual Output of blueberry powder and friut powders is over 240, 0 0 0 tons.
4.Our Certificate

FDA

HALAL

HACCP

ISO

USDA Organic

EU Organic

20+ patents

New High Tech Enterprise
5.Our Team and Exhibition

SOST
Birthday party

FIC
Exhibition

Supplyside West
Exhibition

Brainstorming
Meeting break

CPHI Shaihai
Exhibition

Vitafood Europe
Exhibition

Exhibition visit
Customer meeting

Exhibition negotiation
win-win


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