
Natural L Ergothioneine Pleurotus cornucopiae Extract
Plant origin:Gold Cap Mushroom(Pleurotus cornucopiae)Extract
CAS NO: 497-30-3
MF: C9H15N3O2S
ENIECS NO: 207-843-5
Purity: 1%-5%,customized
Appearance: White Powder
Storage: Cool Dry Place
Overseas warehouse in USA
What is L Ergothioneine Powder?
Natural L-Ergothioneine powder is a unique and powerful antioxidant that has been gaining significant attention in both the health and beauty industries. Ergothioneine, first discovered in 1909 by Charles Tanret in ergots, a type of fungus affecting rye, is naturally produced by certain bacteria and fungi but not by humans or animals. Among natural sources, Pleurotus cornucopiae (also known as the golden oyster mushroom), stands out as an excellent source for extracting ergothioneine.
Ergothioneine functions primarily as a potent intracellular antioxidant, meaning it works effectively within cells to neutralize free radicals and other reactive oxygen species that can cause cellular damage. This ability makes it particularly valuable in combating oxidative stress, which is linked to aging, cardiovascular diseases, neurodegenerative disorders, and cancer. Its role extends beyond mere antioxidation; studies suggest that ergothioneine also plays a part in mitochondrial function, DNA repair, and inflammation reduction.

The golden oyster mushroom (Pleurotus cornucopiae) serves as a natural reservoir of ergothioneine, making it a sought-after ingredient in various applications. As a food ingredient, it offers more than just its antioxidant properties; it's also rich in proteins, vitamins, minerals, and fibers, contributing to overall nutritional value.
Why choose Sost Natural L Ergothioneine Powder?
♦ Pure L-ergothioneine produced through fermentation
♦ The content of Natural L Ergothioneine can be achieved to 5%
♦ Gluten-Free, Non-GMO, Vegan
♦ No added starch, mycelium, or grain of any kind
♦ With the ISO, HALAL, KOSHER, HACCP, the FDA, ORGANIC USDA certificate
♦ Mushroom planting extraction strength factory,contact us freely
Specification
| Spec. | content | Color | Picture |
| L Ergothioneine Powder(Natural) | 5% |
Light Yellow Powder |
![]() |
| L Ergothioneine Powder(synthesize) | 99% | White Powder | ![]() |
COA of L Ergothioneine Powder 5%
|
Items |
Standards |
Results |
|
Physical Analysis |
||
|
Description |
Light Yellow Powder |
Complies |
|
Assay |
L-Ergothioneine ≥ 5.0% |
5.06% |
|
Total Nucleotides ≥ 10mg/g |
11.25mg/g |
|
|
Total Amino Acids ≥ 10.0% |
11.175% |
|
|
Mannitol ≥ 5.0% |
5.16% |
|
|
Mesh Size |
95 % pass 80 mesh |
Complies |
|
Ash |
≤ 5.0% |
3.00% |
|
Loss on Drying |
≤ 5.0% |
4.60% |
|
Chemical |
||
|
Pb |
≤ 2ppm |
Not detected |
|
As |
≤ 2ppm |
Not detected |
|
Cd |
≤ 2ppm |
Not detected |
|
Hg |
≤ 2ppm |
Not detected |
|
Microbiological Analysis |
||
|
Total Plate Count |
≤ 1000cfu/g |
Complies |
|
Yeast&Mold |
≤ 100cfu/g |
Complies |
|
E.coil |
Negative |
Negative |
|
Salmonella |
Negative |
Negative |
Efficacy of natural ergothioneine
Antioxidant Properties
At the core of ergothioneine's efficacy lies its exceptional antioxidant capacity. Unlike many antioxidants that work extracellularly, ergothioneine is unique in its ability to accumulate within cells where it can effectively neutralize free radicals and reactive oxygen species (ROS). This intracellular action helps protect cellular components such as DNA, proteins, and lipids from oxidative damage, which is a key factor in aging and the development of chronic diseases.
Mitochondrial Protection
Ergothioneine plays a critical role in protecting mitochondria-the powerhouses of the cell-from oxidative stress. By stabilizing mitochondrial function, ergothioneine supports energy production and reduces the risk of mitochondrial dysfunction, which is associated with numerous conditions including cardiovascular diseases, neurodegenerative disorders, and metabolic syndrome.

Anti-Inflammatory Effects
Inflammation is a major contributor to many chronic illnesses. Research indicates that ergothioneine exhibits anti-inflammatory properties by inhibiting pro-inflammatory cytokines and reducing oxidative stress. These effects make ergothioneine valuable in managing inflammatory conditions and promoting overall health.
Skin Health
The skincare industry has taken note of ergothioneine's benefits for skin health. As an antioxidant, it shields the skin from environmental aggressors like UV radiation and pollution, preventing premature aging. Additionally, ergothioneine promotes hydration and improves skin elasticity, contributing to a youthful appearance. Products containing ergothioneine are becoming increasingly popular for their ability to nourish and rejuvenate the skin.
Extraction process:
1. As a natural source of ergothionein, Pleurotus auriculatus can produce ergothionein by fermentation. During fermentation, specific amino acids, such as histidine, cysteine, and methionine, need to be added to the medium to optimize ergothionein production. After a certain period of fermentation, the amount of ergothionein in mycelium reaches a high level .
2. The fermentation broth containing ergothionein was heated or treated with alkali to denature the protein. The aim of this step is to release ergothionein from the protein to facilitate subsequent separation and extraction. The treated fermentation broth was subjected to solid-liquid separation to obtain the supernatant containing ergothionein.
3. The obtained clear solution was adjusted to alkaline, filtered through the upper column and membrane, and the precipitated part containing ergothionein could be obtained through solid-liquid separation. The aim of this step is to further purify ergothionein and remove other impurities.
4. After washing the precipitated part obtained, it was dissolved in alkaline solution. Finally, a clear solution of ergothionein was obtained.
Where to buy Natural L Ergothioneine?
If you would like to ask questions about natural L-ergothionine powder and its source or purchase requirements, Just send email to info@sostherbusa.com,we are of service at any time!

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