Stephania Extract Powder

Description

Appearance:Pale yellow
Specification:98%
Test Method:HPLC
Sample:Free Sample
Customized service:Available
Payment method:T/T
Annual supply capacity:1,500 tons
Delivery time:1-3 working days
Certificate:Organic,ISO,Kosher,Halal
Stock:In Stock
Shelf Life:24 Months
Grade:Food/Cosmetic Grade

products detail

Stephania Extract


1.Introduction of Stephania extract


Stephania extract,It is a bipartite isovaline alkaloid isolated from the plant of the family Antibiotics. It has anti-tumor, anti-malarial, anti-bacterial and immune regulating effects. Modern research suggests that it also has the function of stimulating reticuloendothelial system, activating hematopoietic tissue and promoting bone marrow tissue proliferation, and has been clinically used to prevent leukopenia in tumor patients due to radiotherapy, chemotherapy and other reasons, and has received certain effects. It can partially reverse the multidrug resistance of leukemia cells, which is significantly better than the classical reversal drug verapamil, and the cytotoxic effect is much less than verapamil at the reversal dose. Foreign studies have also shown that chikungunin has a good reversal effect on a variety of drug-resistant cells. The immune function activity of cells and macrophages is enhanced in vivo. In Japan, it has been clinically used as a leukocyte-raising drug for more than a year without obvious toxic side effects. In China, it has been used clinically for many years for experimental treatment of pneumoconiosis. The results of the above studies suggest that the clinical use of Chikungunin is of great value.


2.Basic information

Product name

Stephania extract

Specification

98%

Appearance

Pale yellow

CAS Number

481-49-2

Molecular Weight

606.71

Molecular Formula:

C37H38N2O6

Melting Point

145-155°C

Solubility

Dissolved in acetic acid, hydrogenated under palladium catalysis


3.Benefits and function

types of stephania

3.1.Antitumor effects

Stephania extract has potential antitumor effects. Chikungunin alone can exert anti-tumor effects by inhibiting tumor cell proliferation and enhancing the immunity of the body. More promisingly, the combination of chikungunin with chemotherapeutic drugs can improve the efficacy of chemotherapy by reducing cellular resistance. The main mechanism may be that chikungunin interferes with the function of plasma membrane to increase the accumulation of anticancer drugs in cells. In addition, chikungunin has the effect of increasing the sensitivity of tumor cells to radiotherapy.


3.2.Helping women breastfeed their babies

Stephania extract was noted as a remedy used to induce labor. As Stephania extract traveled east, it appeared in Traditional Chinese Medicine documents for issues related to abdominal pain, menstrual cramps, and swelling.


3.3.A leukoproliferative drug that promotes the proliferation of bone marrow tissue, thereby elevating white blood cells. Used in leukopenia. It can increase peripheral blood leukocytes, and animal experiments have found that it can significantly prevent mitomycin-induced leukopenia, but does not inhibit the anticancer effect of mitomycin. Its mechanism of action is to promote the proliferation of bone marrow tissue, thus producing an elevated leukocyte effect. It is used for granulocyte deficiency caused by tumor chemotherapy and radiotherapy and leukopenia caused by other reasons.


4.Application

stephania types

4.1.Used as an analgesic use

4.2.It can be used as a leukocyte proliferation promoting drug. Used in leukopenia. It can increase peripheral blood leukocytes, and animal experiments have found that it can significantly prevent mitomycin-induced leukopenia, but does not inhibit the anticancer effect of mitomycin. Mild gastrointestinal reactions such as nausea, vomiting and diarrhea occasionally.


5.COA


Product Name:Stephania extract

Batch Number:FD20110901 Batch Quantity:125kg

Analysis Date:2021/11/15 Manufacture Date:2021/11/09

Expiry Date:2023/11/08


Items

Standards

Results

Specification(HPLC)

Cepharanthine≥98%

99.38%

Physical Description



Description

Light Yellow to White Powder

Complies

Odor

Characteristic

Complies

Taste

Characteristic

Complies

Particle size

95% pass 80 mesh

Complies

Ash

≤2.0%

0.0076%

Loss on Drying

≤5.0%

1.04%

Chemical Tests



Heavy metals

≤10ppm

Complies

Pb

≤2ppm

Complies

As

≤2ppm

Complies

Cd

≤0.5ppm

Complies

Hg

≤0.1ppm

Complies

Residue on Ignition

Eur.Pharm

Complies

Microbial



Total Plate Count

≤5000cfu/g

Complies

Yeast&Mould

≤100cfu/g

Complies

Staphylococcus

Negative

Complies

Conclusion

Conform to specification.



The Best Stephania extract Supplier:


SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.


Xi an Sost Biotech CO,. Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.


We have 2 factories with area about 40,000 square meters totally, and located in Xi`an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.


Why Choose Sost's Stephania extract?


From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.


We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.


SOST has more than 300 products as our safety stock, free sample can be sent immediately.


Where To Buy Stephania extract?


Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!


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