What foods have nattokinase?
Jan 14, 2026
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In today's fast-paced lifestyle, heart health has become the norm. After much scientific research, the so-called "nattokinase" gradually became public. It is considered a "blood cleanser" due to its unique hemostatic and cardioprotective properties. So what exactly is nattokinase? What foods does it contain? And how should we view this supplement scientifically? This article will answer each of these questions.
What is Nattokinase?
Nattokinase is a serine protease. In short, it is an enzyme with potent biological activity. In 1980, Professor Hiroyuki Sumi, a Japanese scientist, tested over 200 foods in his laboratory at the University of Chicago in search of natural anti-coagulants, and eventually discovered this amazing ingredient in natto. It was discovered that Natto could quickly dissolve artificial blood, even better than some chemicals in use at the time. Since then, nattokinase has become an important area of research in the field of heart health.
What foods contain nattokinase?
To directly answer the question in the title: the main natural source of nattokinase is natto. Natto is a Japanese food made from soybeans fermented by Bacillus subtilis (Natto bacteria). During its fermentation, Bacillus subtilis releases this special enzyme. In addition to natto, there are other fermented soybeans (such as Chinese black bean sprouts) or fermented foods that are also comparable, but with lower content and activity than natto. So if you want to get nattokinase directly from food, eating natto is the best option. But can eating natto effectively support nattokinase? Here we must consider an important scientific fact: the problem of taking nattokinase orally. Although natto contains nattokinase, when we eat it, this bacteria needs a "wake-up call" of stomach acid and digestion. Studies have shown that nattokinase is susceptible to modification and inactivation in a highly acidic environment (acid intestinal pH 1.2–2) and is degraded by intestinal proteases. Therefore, when relying solely on natto intake, the actual nattokinase activity that is absorbed by the body and produces its systemic diuretic effect may be limited. This is why there are special pills or capsules of nattokinase on the market. Special techniques (such as a gastric mask) are often used to shield enzyme activity, allowing it to reach the stomach more efficiently for absorption.

Nattokinase in the human body
Despite the risks associated with absorbing nutrients, several studies have confirmed that the proper supplementation of nattokinase has many benefits for the human body:
1. Blood clotting and blood clotting: This is the main function of nattokinase powder. It can directly break down fibrin, a major component of blood clots, and activate the body's own fibrinolytic system (such as to produce t-PA), which dissolves blood clots, reduces blood viscosity, and improves blood circulation. This is very important in preventing thrombotic diseases such as stroke and myocardial infarction.
2. Helps protect blood pressure and blood lipids: Studies have shown that nattokinase has some effect on lowering blood pressure and lowering lipids. It may help lower blood pressure by inhibiting the enzyme that converts angiotensin, as well as lowering low-density lipoprotein ("bad" cholesterol) and triglycerides, and increasing high-density lipoprotein ("good" cholesterol), which may help prevent atherosclerosis.
Which group of genes needs to be supplemented with nettokinase?
Despite the benefits of nettokinase for vascular health, not everyone needs or benefits from dietary supplements. Special attention should be paid to the following groups:
● High-risk groups for cardiovascular disease: These include people with hypertension, hyperlipidemia, and diabetes (the "big three"), as well as those with a family history of cardiovascular disease. These individuals have a high vascular burden and a lower risk of bleeding.
● Middle-aged and elderly: As we age, the elasticity of blood vessels decreases, the viscosity of blood decreases, and lipids rapidly accumulate on the walls of blood vessels, forming plaque. Middle-aged and elderly individuals are at high risk for thrombotic disease.
● Sedentary or fixed gait: Teens who spend long periods of time sitting at work and not exercising, as well as those who frequently fly long distances (economy class syndrome), are more likely to have increased blood pressure in their lower limbs, resulting in increased blood pressure.
● Individuals experience similar symptoms: frequent dizziness, cold hands and knees, and numbness in the hands, which may indicate poor circulation.

Nattokinase powder manufacturer
If you are a company in the healthcare, food, or pharmaceutical industry and need high quality nettokinase raw materials, Xi'an Sost Biotech Co., Ltd. is a great place to start. it is your trusted assistant.
We are a professional supplier of natural products and bioactive ingredients, dedicated to providing customers worldwide with the highest quality nettokinase products. Our Nattokinase powder is obtained from the highest quality raw materials using advanced biofermentation and extraction technologies for high activity and purity. We pay rigorous attention to every aspect of the production process to meet the strict quality requirements of each customer.
If Nattokinase is required for the manufacture of foods, dietary supplements, or pharmaceutical research, we can supply you with stable and reliable raw materials. We not only provide products but also professional technical support and solutions to help you grow your business.
Contact us:
Email: info@sostherbusa.com
References
[1] The historical background and related research on Professor Hiroyuki Sumi's discovery of nattokinase.
[2] Research on the inactivation of nattokinase in acidic environments and discussions on protective technologies.
[3] Multiple clinical studies confirming the efficacy of nattokinase in dissolving blood clots and improving blood circulation.
[4] Research on the effects of nattokinase in assisting in regulating blood pressure and blood lipids, and its antioxidant properties.
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