Gastrodin Powder

Description

【Appearance】:White to Off-White
【Specification】:98%
【Test Method】:HPLC
【Sample】:Free Sample
【Customized service】:Available
【Payment method】:T/T
【Annual supply capacity】:1,500 tons
【Delivery time】:1-3 working days
【Certificate】:Organic,ISO,Kosher,Halal
【Stock】:In Stock
【Shelf Life】:24 Months
【Grade】:Food/Cosmetic Grade

products detail

Gastrodin


  1.  Introduction of Gastrodin


Tianmain, also known as asparagine, chemically known as 4-hydroxyphenyl-β-D glucopyranoside hemihydrate, API mainly produced in Yunnan Province, China, is a sedative-hypnotic anticonvulsant drug extracted from the dried roots of plants of the genus Orchidaceae, white crystalline powder at room temperature, soluble in water, methanol, ethanol, acetone and hot ethyl acetate, insoluble in ether, asparagine hydrolyzed with bitter almond enzyme. Chemicalbook can get p-hydroxymethylphenidate glycosides. Can restore the balance between cortical excitation and inhibition process imbalance, has a good hypotensive, sedative, hypnotic effect on neurasthenia, insomnia and headache has a certain effect, but also dilate blood vessels, improve myocardial microcirculation, relieve cerebral vascular spasm, increase myocardial nutrient blood flow to improve oxygen supply, is the main drug for the treatment of headache and dizziness, limb numbness, painful convulsions.

 

2. Basic information

Product name

Gastrodin

Specification

98%

Appearance

White to Off-White

CAS Number

62499-27-8

Molecular Weight

286.28

Molecular Formula:

C13H18O7

Melting Point

132-1350 ℃

Solubility

DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Sonicated)

 

3. Benefits and function of Gastrodin

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3.1. With neuroprotective properties

The phenols and glycosides in asparagus have neuroprotective effects. For example, asparagine and 4-HBA can reduce neuroinflammation. It reduces microglia activation and stress in cells (especially in the endoplasmic reticulum). Asparagine can also protect the brain from methamphetamine-induced damage to dopaminergic neurons.

 

3.2. It can prevent neurodegenerative diseases

In the absence of oxygen, tianma can also protect the brain. For example, during a stroke, aspergillus was able to improve overall tissue damage by 67%. In animal models of ischemic stroke, asparagine and 4-HA can reduce the size of stroke and swelling. It also improved recovery after stroke. Asparagine may be beneficial in Alzheimer's disease (AD) because it helps reduce amyloid plaques in the brain and reduces the neurotoxic effects of these plaques. Tianma may help fight inflammation of the spinal cord. For example, tian mao hook and vine soup (GUD) is commonly used in Chinese medicine to treat spinal cord injuries. In Parkinson's disease (PD) models, asparagine significantly and dose-dependently protects dopaminergic neurons from neurotoxicity to prevent dopamine depletion in the brain. 

 

3.3. Improve cognition

Asparagine reduces inflammation in the hippocampus and helps increase its size. Asparagine increases brain-derived neurotrophic factor (BDNF) and glial-derived neurotrophic factor (GDNF). Asparagine (combined with electroacupuncture enhancement) was able to reduce Nogo-A expression. Long-term use of asparagine improved learning and memory in memory-impaired rats.

 

3.4. may help treat epilepsy

Asparagine may prevent seizures and excitotoxicity in the brain by reducing extracellular glutamate levels.

 

3.5. Protect the heart and vascular system

 

Asparagine may protect the heart from myocardial ischemia-reperfusion injury (MIRI). By helping to maintain normal blood flow in the body, asparagus has a protective effect against strokes and heart attacks. For example, asparagus is used in Chinese medicine to treat dizziness, anemia, low blood pressure, and palpitations. Tianma can also lower high blood pressure and improve blood lipid levels. Asparagine may be effective in protecting against cognitive deficits in patients with vascular dementia. By regulating blood flow, asparagine can help treat migraines and headaches. Asparagine and polysaccharide 2-1 have anticoagulant activity, which inhibits clot formation and reduces the risk of thrombosis.

 

4. Application

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4.1.Clinical applications, treatment of dizziness, paralysis, epilepsy, stroke and dementia, and some chronic inflammatory diseases. Asparagine exhibits analgesic effects at the spinal cord level in response to spontaneous pain, mechanical and thermal hyperalgesia induced by peripheral inflammation, which is opioid receptor independent and intolerant. This analgesic effect of asparagine is mediated, at least in part, by blocking acid-sensitive ion channels to inhibit spinal synaptic potentiation。

 

4.2.Pharmacological effects. The application of asparagine or asparagine powder in the preparation of antihepatic fibrosis drugs. For the systematic study of liver histopathological structure of rats, the content of hydroxyproline in rat liver tissue, the oxidative stress response of rat liver tissue and the effect on the degree of liver fibrosis in rats proved that asparagine or asparagine powder has good anti-liver fibrosis activity.

 

4.3. beauty field.

Asparagus is a traditional herb that has been used in Oriental medicine to treat a wide range of neurological disorders (e.g., paralysis and stroke) and skin problems (e.g., atopic dermatitis and eczema). Asparagus shows a dose-dependent inhibition of melanin synthesis through inhibition of tyrosinase activity. Therefore, asparagus may be an effective natural skin lightening agent for use in the cosmetic industry.

 

5.  COA


ANALYSIS ITEM

SPECIFICATION

RESULT

METHOD

Appearance

White powder

Complies

Visual

Odor

Characteristic

Complies

Organoleptic

Assay

Gastrodin≥98%

98.23%

HPLC

Loss on Drying

≤4.0%

2.1%

105℃/3hrs

Ash

≤5.00%

3.29%

Ashing Method

Particle Size

100% pass 80 mesh

Complied

Complied

Residual on Ignition

<1.0%

0.27%

750℃/5hrs

Residual Solvent

Meet the requirements

Conforms

SOP/SA/SOP/SUM/304

Pesticide Residue

Meet the requirements

Not detected

SOP/SA/SOP/SUM/304

Heavy metals




Total Heavy Metals

≤10ppm

Conforms


Arsenic

≤1ppm

Conforms

GF AAS

Lead

≤2ppm

Conforms

AFS

Cadmium

≤1ppm

Conforms

AFS

Hygrargyrum

≤0.1ppm

Conforms

AFS

Microbiological Tests




Total Plate Count

≤5000cfu/g

Conforms

Bacterial culture

Total Yeast & Mold

≤100cfu/g

Conforms

Bacterial culture

E.Coli

Negative

Conforms

Bacterial culture

Salmonella

Negative

Conforms

Bacterial culture

 

The Best Gastrodin Supplier:


SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.


Xi an Sost Biotech CO,. Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.


We have 2 factories with area about 40,000 square meters totally, and located in Xi`an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.


Why Choose Sost's Gastrodin?


From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.


We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.


SOST has more than 300 products as our safety stock, free sample can be sent immediately.


Where To Buy Gastrodin?


Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!


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