Evodiamine Reddit Powder

Description

【Appearance】:Off-white to light yellow solid
【Specification】:98%
【Test Method】:HPLC
【Sample】:Free Sample
【Customized service】:Available
【Payment method】:T/T
【Annual supply capacity】:1,500 tons
【Delivery time】:1-3 working days
【Certificate】:Organic,ISO,Kosher,Halal
【Stock】:In Stock
【Shelf Life】:24 Months
【Grade】:Food/Cosmetic Grade

products detail

Evodiamine Reddit

 

1. Introduction

Evodiline is a naturally occurring indole alkaloid and the main biologically active component of the traditional Chinese medicine Evodiline. It has pharmacological activities such as hypertension-raising effects, antitumor, cardioprotective, weight loss, anti-inflammatory, analgesic, and anti-Alzheimer's. As a new natural anticancer agent, Wu Ju-erucine can inhibit the proliferation of many tumor cells, including those of cervical cancer, colon cancer, lung cancer, melanoma, T-lymphocytic leukemia, prostate cancer, and breast cancer. It also has other biological activities such as thermoregulation, antihypoxia, dermatological applications, bronchoconstriction, and hormone secretion regulation. In addition, wogonidine has good binding ability to a variety of proteins and thus can exert a variety of biological activities as a multi-target compound.

 

2. Basic information

Product name

Evodiline

Specification

98%

Appearance

Off-white to light yellow solid.

CAS Number

518-17-2

Molecular Weight

303.36

Molecular Formula:

C19H17N3O

Melting Point

278 ℃

Solubility

Soluble in acetone, slightly soluble in ethanol, ether, chloroform, almost insoluble in water, petroleum ether, benzene.

 

3.Benefits and function of Evodiamine Reddit

evodiamine reddit 


3.1. Anti-tumor activity

Corydaline can inhibit the proliferation of a variety of tumor cells, including the inhibition of proliferation of cervical cancer, colon cancer, lung cancer, melanoma, T-lymphocyte-like leukemia, prostate cancer and breast cancer. In addition to its anti-proliferative and anti-apoptotic effects, Evodiline can also inhibit tumor invasion and metastasis.

 

3.2. Anti-dementia effect Alzheimer's disease (Alzheimerdisease, AD)

Studies have shown that dogwoodine increases the uptake of glucose by brain tissue and inhibits inflammatory cytokines, but has no effect on amyloid beta protein deposition. Therefore, the effect of Evodiline on improving the behavior of the AD mouse model is thought to be exerted through the inhibition of inflammatory effects. The results of the study showed that dehydrocorydaline, an isoform of corydaline, exhibited more effective biological use against AD, and the chemical structure of dehydrocorydaline has been used in clinical development of new cholinesterase inhibitors.

 

3.3.Effects on the endocrine system

Evodiline can inhibit the activity of steroid hormone production-related enzymes such as 3β-hydroxysteroid dehydrogenase (3β-HSD) by decreasing the activity of intracellular cyclic adenosine monophosphate (cAMP)-related pathways, reducing and affecting signal transduction and RNA-activated protein (StAR) expression, and inhibiting corticosterone secretion by acting directly on rat adrenal cortex bundle reticular cells. 10-4 mol-L- 1 Wujusine incubated rat testicular interstitial cells (TICs) for 1, 2 and 4h effectively reduced the basal level of testosterone as well as human chorionic gonadotropin-stimulated testosterone secretion and inhibited forskolin-induced testosterone release. Evodiline base can also inhibit 8-Br-cAMP and androstenedione induced testosterone release.

 

3.4. Hypoglycemic effect

Evodiline reduces obesity serum total cholesterol and triglyceride levels. Evodiline can reverse obesity complications of vascular hypertrophy. The mechanism of action may be related to the regulation of CGRP and TRPV1 expression in serum, vascular tissue and DRG.

 

3.5. Effects on cardiovascular system

Evodiline can produce indirect excitatory and direct inhibitory effects on cardiac tissues. The hypotensive effect of dogwood alkaloids is achieved through diastolic endothelial cells and smooth muscle cells, and can affect aldosterone release by inhibiting the activity of 11-hydroxylase, which is involved in aldosterone steroid synthesis, thereby affecting blood pressure. The methanolic extract of Cornus officinalis and three quinolone alkaloids significantly inhibited vascular tension and regulated blood pressure efficacy.

 

4.Application

evodiamine 


4.1.Weight loss.

 Not only does Evodiline  help your body burn more calories, but it also prevents your body from producing new fat cells. Studies have shown that Corynoline reduces pre-fat cell differentiation. The main reason you will see cornelian in supplements (especially fat burners), for example, is that it raises body temperature, such as thermogenesis before a workout, which helps your body burn more calories and ultimately lose weight.

 

4.2. Drugs - Anti-inflammatory

Evodiline  can dose-dependently inhibit the expression of epoxide dismutase (COX-2) and nitric oxide synthase (iNOS) and reduce the release of prostaglandins (E2). The number of torsions induced by acetic acid was significantly inhibited. The isolated ileum of mice given Evodiline  lost the response to sensory nerve stimulation and retained the response to vagal nerve stimulation, and Evodiline exerted analgesic effects through sensory nerve desensitization.

 

4.3Beauty.

Corydaline has a stimulating effect on the microcirculation of the skin - this results in a revitalized, radiant complexion. It is also a powerful anti-inflammatory, soothing irritated, sensitive skin and reducing redness. It can even reduce the skin's sensitivity to environmental stress and pollution


5.COA

Analysis Items

Specifications

Test Methods

Appearance & Color

Fine brown yellow powder

Visual

Odor & Taste

Characteristic

Organoleptic

Mesh Size

NLT 90% through 80 mesh

80 Mesh Screen

Assay

98%Evodiamine (HPLC)

98.12%

Method of Extraction

Hydro-alcoholic

/

Extract Solvent

Grain alcohol/Water

/

Moisture Content

NMT 5.0%

5g / 105℃ / 2hrs

Ash Content

NMT 5.0%

2g / 525℃ / 3hrs

Heavy Metals

NMT 10ppm

Atomic Absorption

Arsenic (As)

NMT 1ppm

Atomic Absorption

Cadmium (Cd)

NMT 1ppm

Atomic Absorption

Mercury (Hg)

NMT 0.1ppm

Atomic Absorption

Lead (Pb)

NMT 3ppm

Atomic Absorption

Sterilization Method

High Temperature & High Pressure for short time (5” – 10”)


Total Plate Count

NMT 10,000cfu/g

Complied

Total Yeast & Mold

NMT 1,000cfu/g


E. Coli

Negative

Negative

Salmonella

Negative

Negative

Staphylococcus

Negative

Negative

  

The Best Evodiamine Reddit Supplier:


SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.


Xi an Sost Biotech CO,. Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.


We have 2 factories with area about 40,000 square meters totally, and located in Xi`an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.


Why Choose Sost's Evodiamine Reddit?


From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.


We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.


SOST has more than 300 products as our safety stock, free sample can be sent immediately.


Where To Buy Evodiamine Reddit?


Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!


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