What Makes Alisma Extract a Magical Food Material?

 

 

1. Blood lipid-lowering effect Alisma extract, alcoholic extract and alcoholic extract, etc., have preventive and therapeutic effects on experimental hyperlipidemia in rabbits. It can prevent and inhibit the formation of total experimental aortic atherosclerotic plaque, and alleviate its development. Alisma can reduce various lipids in the aorta, especially cholesterol, which can lead to the reduction of aortic plaque. Intraperitoneal injection of the fat-soluble part of Alisma has the effect of clarifying plasma lipids in rats with hyperlipidemia caused by oral administration of cottonseed oil; it has obvious cholesterol-lowering and anti-atherogenic effects on hypercholesterolemia in experimental animals hardening effect. Its active ingredients are alisitol A and acetates of A, B, and C, especially alisitol A acetate has the strongest effect. Alisitol A can inhibit the absorption of cholesterol in the small intestine of rats, and inhibit the ability of cholesterol esterification in the small intestine of mice.

 

2. Liver protection and anti-fatty liver effect Alisma extract can reduce the fat content in the liver of rabbits fed with cholesterol and high fat, and the choline, lecithin, amino acid and phenyl-acetone soluble part T contained in the extract have Anti-fatty liver effect, has protective effect on acute liver injury caused by carbon tetrachloride, can inhibit the accumulation of fat in the liver, inhibit the decline of phospholipids in plasma and liver, and improve the excretion function of liver pigment. Alisma can significantly reduce the content of total cholesterol, cholesteryl ester, triglyceride and total ester in the liver of experimental hyperlipidemia animal model. Alisma can reduce the Lee index of experimental obese rats, the fat index of the uterus and testis, and the content of serum triglycerides. The mechanism of action may be caused by affecting the enzymes related to cholesterol metabolism and inhibiting the synthesis of triglycerides in the liver.

 

3. Diuretic effect Alisma extract has a diuretic effect on humans and animals, which can increase the excretion of sodium, chloride, potassium and urea in urine. Intraperitoneal injection of Alisma liquid extract can reduce the retention of urea and cholesterol in the blood of rabbits with nephritis caused by nitroglycerin. The potassium content in Alisma is as high as 147.5mg%, which can significantly increase the excretion of urinary potassium in adrenalectomy rats. Alisma ethanol extract has a dose-dependent inhibition of renal Na+, K+-ATPase activity.

 

4. Effects on the cardiovascular system Alisma extract, given intravenously to dogs or rabbits, has a mild antihypertensive effect Chemicalbook. In vitro, it has a slow relaxing effect on the contraction of isolated rabbit aortic strips induced by epinephrine. Alisma alcohol extract can significantly expand the coronary artery in isolated rabbit heart, has no antagonism effect on myocardial ischemia caused by vasopressin, and has a mild inhibitory effect on myocardial contractility. Oral or intraperitoneal administration of alisolol has a long-lasting and moderately strong antihypertensive effect on rat models of DocA hypertension, renal hypertension and essential hypertension. Alisma has a significant inhibitory effect on platelet aggregation, and it can significantly enhance its inhibitory effect on platelet aggregation when used together with hawthorn.

 

5. Effects on the immune system Alisma water decoction can significantly inhibit the carbon particle clearance rate and DNCB-induced contact dermatitis in mice, but has no significant effect on mouse IgG content and SRBC-induced mouse delayed footpad swelling. Alisexin extracted from Alisma has a selective effect on the aggregation of human erythrocytes and mouse spleen lymphocytes and the inhibition of macrophage migration. Both human and guinea pig erythrocytes can be aggregated by alisexin, which has no blood group specificity The aggregation of spleen lymphocytes in mice is similar to that of ConA, but slightly stronger than that of PHA.

 

6. Anti-inflammatory effect Alisma decoction can significantly reduce the ear swelling of mice caused by xylene, and inhibit the hyperplasia of rat cotton ball granulation tissue, but has no significant effect on serum antibody levels and rat adrenal gland ascorbic acid levels.

 

7. The ability to scavenge free radicals The research shows that Alisma alisma n-butanol extract, ethyl acetate extract and water extract have a strong ability to scavenge free radicals.

 

8. Anti-kidney stone formation. Giving the hot methanol extract of Alisma alisma to rats with immune complex (IC) nephritis at 200 mg/kg per day for 20 consecutive days can inhibit urinary protein excretion, glomerular cell infiltration, and renal tubular degeneration and regeneration, and inhibited the occurrence of various complications in rats with IC nephritis, indicating that Alisma alisma has significant anti-nephritis activity.

 

9. Other effects The subcutaneous injection of Alisma extract has mild hypoglycemic effect in rabbits. Alisma decoction has an antagonistic effect on the spasm of rabbit muscles caused by acetylcholine, can moderately increase the coronary flow of rabbit heart and relax isolated rabbit thoracic aortic smooth muscle, and has a slight inhibitory effect on myocardial contractility.

 

 

 

 

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