Is Andrographis Extract Effective Against COVID-19?

Mar 24, 2022

Andrographis extract is a strong products of Xi an Sost Biotech Co,. Ltd. Called fah talai jone in Thai and “the king of bitters,” among other names, andrographis is a small annual plant. In India’s traditional medical system of Ayurveda, the plant’s dried leaves and shoots are used for bronchitis, cough, diarrhea, dyspepsia, fever, inflammation, and skin diseases. In traditional Chinese medicine, the plant has been used to treat colitis, cough, dysentery, fever, influenza, and sore throat. Modern studies have focused on andrographis’ potential benefits for respiratory and digestive conditions. However, that’s not all it does. 

Andrographis Extract


Until the  end of  2019, COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 has posed an enormous threat to public health worldwide. Andrographidine C (MOL008223) and andrographolide (MOL008232) were found with strong binding affinity to the target active sites of the potential targets by molecular docking.This research identified novel molecules against COVID-19 for developing natural medicines from Andrographis paniculate. A research report first published on 11th November 2021 by Royal Society Chemistry says that an andrographolide sulfonates preparation, named Xiyanping injection in Chinese, which was prepared from the aqueous extract of Andrographis paniculata, showed favorable therapeutic effectiveness on COVID-19, suggesting Andrographis paniculata could contain powerful therapeutic ingredients against COVID-19.

andrographis paniculata powder


In late August 2020, The Nation Thailand reported that the lower dose of andrographis showed benefits in the preliminary trial, especially for coughing. Within three days, both cough volume and overall symptom severity reportedly decreased significantly. After five days, other symptoms improved, and real-time polymerase chain reaction (PCR) tests were negative for the COVID-19 virus in two patients. After three weeks, real-time PCR tests were negative in all six subjects. In late December 2020, the government of Thailand approved a pilot study of the use of the southern Asian herb andrographis to treat early symptoms and reduce the severity of COVID-19.

andrographis paniculata extract



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