Can Shilajit Extract Reduce Inflammation?
Nov 04, 2025
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Currently, the evidence is limited. Shilajit extract powder is not a substitute for conventional medications, but it can be used to relieve stress and anxiety."Adaptogenic" has been the most popular name in the pharmaceutical industry for the past five years. Shilajit, along with Ashwagandha, Rhodiola rosea, and basil, is considered one of the "Big Four."
However, "adaptogenic" is not the same as "anxiolytic." The key point is to look at the previous and non-clinical studies: Animal behavior: In 2022, two studies published in the *Journal of Ethnopharmacology* showed that after administration of 25 mg/k and 14 mg plasma and 50 mg water of ostrich, the corticosterone test score was 28%, suggesting anxiolytic activity.
At the cellular level: Shilajit extract fulvic acid is an important feature of Shilajit (a popular Chinese herb), which can cross the blood-brain barrier, reduce mast cell degranulation, and inhibit neuroinflammation, so it is considered one of the most effective ways to relieve pain.
In humans: Although it has not yet entered advanced phase III trials, a randomized, double-blind study conducted in Canada in 2023, involving 82 participants, showed that daily administration of 500 mg of Shilajit extract (≥40% fulvic acid) increased the effects by 8 seconds. The HAMA level was significantly better than in the placebo group (p < 0.05).
What are the reported results for the top and best-selling bottles of Shilajit products?
A search for "Shilajit supplement" on Amazon and TikTok reveals 12 brands priced between $39.90 and $69 per bottle. The six most common are:
○ Overcoming fear and anxiety
○ Boosting energy and mitochondria
○ Hormonal changes
○ Increased knowledge and education
○ Boosts immunity
○ Anti-aging and glowing skin
9 products boast "Stress and anxiety free" on their packaging, along with "100% pure Himalayan Shilajit" and "Fulvic acid ≥ 60%. It is important to note that the approval of Shilajit extract powder in China only allows for activities such as "reducing appetite, improving hypoxia resistance, and increasing metabolism" and does not include "alleviating anxiety or depression." Therefore, foreign investors use "Stress relief" instead of "Anti-anxiety" to reduce regulatory differences between countries.

What is the difference between Shilajit extract powder and Shilajit resin?
**Physical differences:**
Shilajit extract Extract: A thin, white, powdery substance containing 10%-70% fulvic acid. These can be crushed into tablets or dissolved into capsules and mixed with other medications.
Shilajit Resin: A "resin" containing 30%-70% fulvic acid. It is heated in hot water to 40°C and a cola-colored liquid is obtained. It is commonly used in sparkling water, cocktails or even in small flavor sachets.

**Information difference:**
Animal studies have shown that at the same concentration, the Cmax of plasma fulvic acid in the extract group was 1.7 times higher than that in the control group, while the Tmax was lower at 0.5 hours, indicating better biodistribution. Counterterrorism
In the "chronic stress + elevated maze" model, the treatment (100 mg/kg) and the synthetic (200 mg/kg) appeared simultaneously, indicating that the activity of the exposed animal was twice that of the synthetic; however, when expressed as "fulvic acid content per unit", there was no significant difference between them.
Who can supply raw materials for Shilajit extract?
Sost Biotech has focused on raw materials for Shilajit products for 12 years.
We own a 3000㎡ GMP cleanroom with an annual production capacity of 120 tons of extract and 60 tons of paste.
Fulvic acid content is available in a full range of 10%–70%, with customization options for particle size, bulk density, and solubility.
We source directly from the 3200-meter Himalayan vein, ensuring heavy metal content is ≤0.3 ppm. We have passed ISO22000, HACCP, HALAL, KOSHER, and USDA ORGANIC certifications for 8 consecutive years.
We maintain a stock of 50 kg–500 kg in various specifications, available for FOB, CIF, and DDP shipments to multiple ports worldwide.
We welcome inquiries from brands, OEMs, and cross-border e-commerce companies. Free samples and a complete set of COA/MSDS/stability data are available.
Email: info@sostherbusa.com
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