Chrysanthemum Parthenium Extract 1% Parthenolide

what is Chrysanthemum Parthenium Extract Parthenolide?

Chrysanthemum Parthenium Extract Parthenolide is a sesquiterpene lactone that is abundantly present in the leaves and flowers of feverfew (Tanacetum parthenium).Parthenolide possesses a variety of important pharmacological activities, such as anti-tumor, antiviral, anti-inflammatory, and anti-atherosclerotic effects.Traditionally, it has been primarily used to treat fever, migraines, skin infections, and rheumatoid arthritis.

Extraction methods: Feverfew lactones are typically extracted from plant materials using solvent extraction, ultrasound-assisted extraction, or microwave-assisted extraction methods. Further purification is then achieved through techniques such as column chromatography and gel filtration to obtain high-purity feverfew lactones.

Chrysanthemum Parthenium Extract Parthenolide benefits

● It initially halves the frequency of migraine attacks because it directly blocks 5-HT release at nerve endings, preventing cerebral blood vessels from constricting erratically.
● Chrysanthemum Parthenium Extract Parthenolide then shortens the duration of morning stiffness in joints; it penetrates synovial cells, alkylating the Cys179 switch of NF-κB, immediately reducing the production of IL-1β and TNF-α mRNA.
●Parthenolide can also reduce redness in sunburned skin overnight; a 0.3% concentration neutralizes ROS and blocks COX-2, reducing the erythema area by 40% the next day.
●In the gut, parthenolide acts like a gardener: it nourishes butyrate-producing Alloprevotella bacteria. As butyrate concentration increases, the number of Treg cells doubles, Th17 cells are suppressed, and colitis scores decrease significantly.
●In tumors, parthenolide transforms into an assassin: it simultaneously targets IKKβ and p65, halting the production of anti-apoptotic proteins, and then uses alkylation to disrupt microtubules, halting cancer cell division midway.
●In a cerebral ischemia model, pre-treatment with parthenolide for one week reduces infarct volume by one-third because it suppresses ROS, restores SOD activity, and maintains the integrity of neuronal membranes.

COA

How to use parthenolide?

□ For migraine sufferers, chewing one dried leaf containing 0.7% parthenolide daily reduces the frequency of attacks month by month.
□ For oily, sensitive skin, applying a gel containing 0.2% parthenolide to blemishes after washing the face reduces redness and swelling within three days.
□ After sun exposure during travel, adding two drops of parthenolide microemulsion to your evening serum prevents makeup from caking the next day.

How to choose Chrysanthemum Parthenium Extract Supplier?

SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.

Xi'an Sost Biotech Co., Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.

We have 2 factories with area about 40,000 square meters totally, and located in Xi'an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.

2.Why Choose Sost?

From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.

We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.

SOST has more than 300 products as our safety stock, free sample can be sent immediately.

3.Where To Buy?

Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!

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