Bilirubin Powder

Bilirubin Powder

Appearance:Red powder
Specification:99%
Test Method:HPLC
Sample:Free Sample
Customized service:Available
Payment method:T/T
Annual supply capacity:1,500 tons
Delivery time:1-3 working days
Certificate:ISO,Kosher,Halal
Stock:In Stock
Shelf Life:24 Months
Grade:Food/Cosmetic Grade
Send Inquiry

Bilirubin Powder

1. Introduction of Bilirubin Powder:

Bilirubin ( BR ) (Latin for "red bile") is an orange-red compound that is present in the normal catabolic pathway that breaks down hemoglobin in vertebrates. This catabolism is a necessary process for the body to remove waste products resulting from aging or abnormal red blood cell destruction. In the first step of bilirubin synthesis, the heme molecule is stripped from the hemoglobin molecule. Hemoglobin is then catabolized through a variety of processes in porphyrins, which vary depending on the area of the body where catabolism occurs. For example, the molecules excreted in the urine are different from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which biliverdin reductase performs the second step, producing bilirubin from biliverdin. Eventually, bilirubin is broken down in the body and its metabolites are excreted through bile and urine; elevated levels may indicate certain diseases. It is responsible for healing the yellow color of bruises and the yellow discoloration of jaundice. Its breakdown products, such as fecal bilirubin, cause brown coloring of the stool. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.

Although bilirubin is usually found in animals rather than plants, at least one plant, cranberry, is known to contain this pigment.

                                                            Bilirubin Powder2

 

2. Basic information

Product name

Bilirubin

Specification

99%

Appearance

Red powder

Melting point

641.7°C

CAS Number

635-65-4

Molecular Weight

 584.66

Solubility

Practically insoluble in Chloroform, benzene, chlorobenzene

 

3.Benefits and function of Bilirubin Powder:

initpintu1_ 

 

3.1. Antioxidant activity

Bilirubin is produced by the activity of biliverdin reductase on biliverdin, a green tetrapyrrole bile pigment and a product of heme catabolism. Bilirubin reverts back to biliverdin again after it has been oxidized. This cycle, in addition to demonstrating the potent antioxidant activity of bilirubin, led to the hypothesis that the primary physiological role of bilirubin is as a cellular antioxidant. In line with this, animal studies have shown that elimination of bilirubin leads to endogenous oxidative stress. The antioxidant activity of bilirubin may be particularly important in the brain, where it prevents excitotoxicity and neuronal death by scavenging superoxide during N-methyl-D-aspartate neurotransmission.

 

3.2. Pharmacological effects

Bilirubin has a variety of pharmacological effects and is the main raw material for the manufacture of artificial bilirubin. Pharmacological experiments have proved that it has a good inhibitory effect on W256 tumor, and the inactivation rate and inhibition index of B encephalitis virus is 1-1.5 times higher than that of deoxycholic acid and bile acid; it also is an effective therapeutic drug for liver diseases, which has the effect of proliferating new cells without destroying liver tissues, and can treat serum hepatitis and liver sclerosis, etc. In addition, bilirubin has sedative, analgesic, antipyretic, antihypertensive, promote red blood cell neonatal and other effects.

 

3.3. The role of bilirubin in the liver

Bilirubin is produced during the normal process of breaking down red blood cells. It is a yellowish substance found in bile, which is a fluid in the liver. This fluid helps digest food. A healthy liver will remove most of the bilirubin from your body. If the liver is damaged, bilirubin may leak into the bloodstream, resulting in jaundice, which is characterized by yellowing of the skin and eyes, among other symptoms. Therefore, a bilirubin test that measures these levels can help health care providers screen for diseases that affect the liver.

 

4.Application of Bilirubin Powder:

initpintu_ 

 

4.1.For the determination of bilirubin in artificial cow's milk, preparation of artificial cow's milk and biochemical studies.

 

4.2.Biochemical studies. Analytical chemistry. Biochemical studies. Synthesis of bovine flavors. Antioxidant, protects membrane phospholipids from oxidation by hydrogen peroxide radicals. Protects neurons from oxidative damage even at nanomolar concentrations

Major pigment of bile; functions as an antioxidant as well as an effective scavenger of hydrogen peroxide radicals, protecting cell membrane lipids from oxidation by these reactive radicals.

 

4.3. Clinical applications. Bilirubin has an important role in a variety of clinical applications. Bilirubin has antioxidant, anti-inflammatory and immunomodulatory properties. Bilirubin/biliverdin is used as a photoactive component for therapeutic diagnosis. Bilirubin nanodrugs increase the solubility, stability and targeting of the drug. Bilirubin acts as a multifunctional component for building nanostructures. Bilirubin is influenced by many factors such as smoking, age, gender, fasting status, alcohol consumption and undiagnosed liver disease, which may account for the discrepancy in the results of some studies. For these reasons, there is potential heterogeneity in the critical values of serum bilirubin that can be used in clinical practice. Therefore, there is a great need for larger, prospective and possibly randomized controlled trials to clearly characterize the role of bilirubin in various disease processes.

 

5.COA


Product name:Bilirubin                       Batch:DHS20211119

Manufacture date: Nov 19 2021         Expiry date:Nov 18 2023

ANALYSIS ITEMS

SPECIFICATIONS

METHODS

Characteritics



Appearance

Red powder

Visual

Odor

Odorless

Sensory

Taste

/

Sensory

Physical & Chemical



Inulin

≥90.0g/100g

FCC IX

Fructose+Glucose+Sucrose

≤10.0g/100g

FCC IX

Loss on drying

≤4.5g/100g

USP 39<731>

Residue on ignition

≤0.2g/100g

USP 39<281>

pH (10%)

5.0-7.0

USP 39<791>

As

≤0.2mg/kg

USP 39<233>ICP-MS

Pb

≤0.2mg/kg

USP 39<233>ICP-MS

Hg

<0.1mg/kg

USP 39<233>ICP-MS

Cd

<0.1mg/kg

USP 39<233>ICP-MS

Microbiological Control



Total Plate count

≤1,000CFU/g

USP 39<61>

Yeasts&Moulds count

≤50CFU/g

USP 39<61>

E.coli

Negative

USP 39<62>

Salmonella

Negative

USP 39<62>

S.aureus

Negative

USP 39<62>

 

The Best Bilirubin Powder Supplier:


SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.


Xi an Sost Biotech CO,. Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.


We have 2 factories with area about 40,000 square meters totally, and located in Xi`an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.


Why Choose Sost's Bilirubin Powder?


From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.


We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.


SOST has more than 300 products as our safety stock, free sample can be sent immediately.


Where To Buy Bilirubin Powder?


Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!


1_


3_

4_


5_

Bilirubin Powder is in our stock contact us now get a sample now! 

Hot Tags: bilirubin powder, China bilirubin powder manufacturers, suppliers, factory, pure turmeric extract curcumin, pure Matcha Tea Powder, Instant Black Tea Extract Powder for sale, organic Raw Vitamin C Powder, Buy Green Papaya Powder, green papaya powder

Send Inquiry