Sophora Flavescens Extract Powder

Sophora Flavescens Extract Powder is an alkaloid extracted from Sophora flavescens, a plant of the genus Sophora flavescens. The root of the raw material is tough, the section is thick and fibrous, yellowish white. Slight gas, extremely bitter taste.

Sophora Flavescens Extract Powder has various effects such as whitening, anti-inflammatory, anti-acne, antibacterial, etc. It has been used for beauty and skin care hundreds of years ago, and now it is a cosmetic raw material favored by major cosmeceuticals.

Sophora Flavescens Extract Powder is the extract of Sophora flavescens, a leguminous plant, and the main active ingredient, oxymatrine, contains more than 98%. It has the functions of clearing away heat and dampness, killing insects and diuresis. It is used for dysentery, blood in the stool, jaundice and anuria, red and white vaginal discharge, pruritus vulvae, eczema, eczema, skin itching, mange and leprosy, external treatment of trichomonal vaginitis.

Function cures mainly: heat-clearing and damp-drying, desinsection diuresis. Indications for hot dysentery and blood in the stool, jaundice, red urine, red and white vaginal discharge, vulvar swelling and itching.

1. Protect gastric mucosa
Sophora flavescens extract has a significant protective effect on gastric mucosal damage caused by hydrochloric acid, ethanol, and indomethacin, and its main components are flavanone compounds. Recent studies have shown that matrine is also one of the active ingredients of matrine in resisting gastric mucosal damage, and it has a significant effect on gastric mucosal damage caused by stress, hydrochloric acid, ethanol, and indomethacin in rats. Protective effects. It shows that Sophora flavescens may have certain anti-ulcer effect.

2. Anti-inflammatory effect
Matrine has a significant antidote to acute exudative inflammation caused by various inflammatory agents (croton oil, glacial acetic acid, carrageenan, egg white), similar to hydrocortisone. Its anti-inflammatory mechanism has nothing to do with the pituitary-adrenal cortex system, and matrine still has a significant anti-inflammatory effect on adrenalectomy mice. Studies have shown that this product has non-steroidal anti-inflammatory drug properties. In addition, matrine has a stabilizing effect on red blood cell membranes, and drugs that have a stabilizing effect on red blood cells often have a stabilizing effect on lysosomal membranes, thereby reducing the release of inflammatory mediators and achieving anti-inflammatory purposes.

3. Anti-tumor effect
Matrine mice were injected intraperitoneally with 500 μg/day, and the survival rate was 40%, while the control group all died within 23 days. Oxymatrine has no effect on this. Matrine has the effect of reducing mouse peritoneal macrophages and inhibiting the proliferation of P815 tumor cells in vitro. Sophocarpine also has anticancer activity. Matrine, oxymatrine, sophocarpine and their mixed bases A, B, and C in different proportions all have different degrees of inhibitory effects on S180 solid tumors. Matrine has a significant inhibitory effect on the production rate of peripheral multitropic hematopoietic progenitor cell colonies in chronic myelogenous leukemia. Sophora flavescens water decoction acts on human promyelocytic leukemia cells cultured in vitro, and can significantly induce the differentiation of leukemia cells into mononuclear macrophages.

4. Raising white blood cells
Oxymatrine can prevent mice from leukopenia caused by MMC and cyclophosphamide, and intravenous or intramuscular injection of total matrine and oxymatrine can significantly increase the number of peripheral blood leukocytes in normal rabbits , and compared with total matrine, the effective time, maintenance time and peak value of white blood cell count of oxymatrine on the whitening effect of normal rabbits are basically the same within 18 days after administration, and the whitening effect is better than that of shark liver alcohol.

5. The effect on the cardiovascular system
Intravenous injection of matrine and oxymatrine significantly antagonized aconitine and chloroform-epinephrine-induced arrhythmia in rats; intraperitoneal injection significantly antagonized Chemicalbook chloroform-induced ventricular fibrillation in mice, and also improved aconitine-induced rat arrhythmia The dosage required for arrhythmia is against barium chloride-induced arrhythmia in rats and arrhythmia induced by ligation of the anterior descending coronary artery in rats.

6. Anti-asthma and expectorant effect
Matrine produces anti-asthma effect mainly by stimulating β-receptors, especially the β-receptors in the excitatory center, relieving bronchospasm and inhibiting the release of antibodies and slow-reacting substances.

7. Stabilization
Matrine total alkaloids can significantly inhibit the free activities of mice; significantly inhibit the passive activities of mice; high doses can inhibit the fighting behavior of lonely mice.

8. Anti-allergic effect
Matrine can reduce the release of allergic mediators, and its concentration of inhibiting 50% OT cell proliferation is 0.55-0.56 mg/ml; the concentration of inhibiting IL-2 production is 0.1 mg/kg.

9. Immunosuppressive effect
Both matrine and oxymatrine have inhibitory effects on the immune function of mice.

10. Antifungal effect
Sophora flavescens decoction has inhibitory effect on common skin fungi.

11. Antibacterial effect
Sophora flavescens extract has inhibitory effects on Staphylococcus, Pseudomonas aeruginosa, Mycobacterium tuberculosis and so on.

12. Effects on the central nervous system
When matrine was injected into rabbits, the central nervous system was found to be paralyzed, convulsions occurred at the same time, and eventually respiratory arrest and death occurred. Injected into frogs, they are excited at first, then paralyzed, breathing becomes slow and irregular, and then convulsions occur, resulting in death due to respiratory arrest. The convulsions may be caused by hyperreflexia of the spinal cord.

13. Antiarrhythmic effect
Sophora flavescens has a good resistance to arrhythmia caused by aconitine, sympathetic amine, and digitalis poisoning, and its effect is quite similar to quinidine. That is, by affecting the potassium and sodium conduction system of the myocardial cell membrane, the absolute refractory period of the myocardium is prolonged and the stress is reduced, thereby inhibiting the ectopic pacemaker and exerting an antiarrhythmic effect. Its active ingredient is preliminarily proved to be the alkaloid part contained. Because Sophora flavescens has no effect on the myocardial contractility and heart rate of frog hearts and rats in vivo, and does not increase myocardial oxygen consumption and aggravate heart failure and shock, it is worth paying attention to ischemic heart disease.

Advantages

1.The Best Supplier

SOST Biotech is a manufacturer with more than 17 years exporting herbs extract powder in China.

Xi an Sost Biotech CO,. Ltd. is the leading manufacturer in research, development, production, sale and service of cosmetic ingredients, healthcare ingredients, fruits & vegetables powder, food additives and active pharmaceutical ingredients(API), as well as Chinese medicine raw material. We insist on producing high quality, green products for human health. Building mutually beneficial and win-win partnership as our development strategy.

We have 2 factories with area about 40,000 square meters totally, and located in Xi`an, Shaanxi, China with convenient transportation.The factory is close to the rich vegetation of the Qinling Mountains, a treasure trove of unique plant resources, providing the company with high-quality raw materials.

2.Why Choose Sost

From selection of raw material, extraction to finished products, we produce standardized plant extract strictly complied with GMP standard, HACCP, EU USDA organic, ISO, SC, SGS requested.Complied with Kosher, Halal,FDA registration.

We offer competitively priced products that have third-party inspection reports to ensure they are safe to use worldwide. If you are not satisfied with what you have received, we can provide hassle-free returns and exchanges.

SOST has more than 300 products as our safety stock, free sample can be sent immediately.

3.Where To Buy

Just send email to info@sostherbusa.com, or submit your requirement in bottom form, we are of service at any time!

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